Abstract
One hundred fifty-five inborn infants with a birth weight <- 1,500 gm were prospectively evaluated for germinal layer/intraventricular hemorrhage. Maternal characteristics, obstetric factors, and neonatal condition in the immediate newborn period were analyzed as possible risk factors for germinal layer/intraventricular hemorrhage. Early germinal layer/intraventricular hemorrhage or hemorrhages identified during the first 24 hours of life were observed in 85 (55%) of these infants. Another 37 (24%) had germinal layer/intraventricular hemorrhage after 24 hours of age (late germinal layer/intraventricular hemorrhage). None of the maternal and obstetric variables, including labor, mode of delivery, and presentation, appeared to increase the risk of germinal layer/intraventricular hemorrhage. The immediate neonatal condition, birth weight, gestational age, and intrauterine growth, all influenced the occurrence of germinal layer/intraventricular hemorrhage, especially early germinal layer/intraventricular hemorrhage. We suggest that future studies to investigate the role of maternal or obstetric factors in the pathogenesis of germinal layer/intraventricular hemorrhage should discriminate early from late germinal layer/intraventricular hemorrhage. Obstetric factors are more likely to influence the early onset of germinal layer/intraventricular hemorrhage; their effect, if any, becomes less discernible later.
Original language | English |
---|---|
Pages (from-to) | 798-804 |
Number of pages | 7 |
Journal | American Journal of Obstetrics and Gynecology |
Volume | 148 |
Issue number | 6 |
DOIs | |
State | Published - Mar 15 1984 |
Bibliographical note
Funding Information:From the Departments of Pediatrics, Obstetrics and Gynecology, and Radiology, The University of Tennessee Center for the Health Sci-ences, and the Department of Mathematical Sciences, Memphis Stale University. Supported in part by the March of Dimes Birth Dejects Foundation Research Grant No. 6-297. ReceivedforpublicationJune 13,1983. Revised September 23, 1983. Accepted October 5, 1983. Reprint requests: Henrietta S. Bada, M.D., Newborn Center, 853 Jefferson, Room 301, Memphis, Tennessee 38163.
ASJC Scopus subject areas
- Obstetrics and Gynecology