Orbital sarcoma with metastases at diagnosis: A report from the soft tissue sarcoma committee of the children's oncology group

Winston W. Huh, James R. Anderson, David Rodeberg, Lisa Teot, Torunn Yock, R. Beverly Raney

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We reviewed clinicopathologic features and treatment outcomes in seven patients diagnosed with Stage 4/Group IV orbital sarcoma and treated on IRSG protocols I-III. Three patients had embryonal rhabdomyosarcoma (RMS), and two patients each had alveolar RMS or unclassified sarcoma. Median age at diagnosis was 1.8 years (range 0.2-6.9 years). All patients had bone marrow involvement, including six with normal complete blood count at diagnosis. Cerebrospinal fluid was normal in six patients. Three patients survived >5 years, including one with local recurrence. In conclusion, further study is needed to determine necessity of bone marrow and CSF examination in orbital sarcoma patients.

Original languageEnglish
Pages (from-to)1045-1047
Number of pages3
JournalPediatric Blood and Cancer
Volume54
Issue number7
DOIs
StatePublished - Jul 1 2010

Funding

FundersFunder number
National Childhood Cancer Registry – National Cancer InstituteU10CA098543

    Keywords

    • Metastasis
    • Orbit
    • Pediatric
    • Rhabdomyosarcoma
    • Sarcoma

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Hematology
    • Oncology

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