TY - JOUR
T1 - Oropouche virus
T2 - Clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus
AU - Travassos Da Rosa, Jorge Fernando
AU - De Souza, William Marciel
AU - De Paula Pinheiro, Francisco
AU - Figueiredo, Mário Luiz
AU - Cardoso, Jedson Ferreira
AU - Acrani, Gustavo Olszanski
AU - Teixeira Nunes, Márcio Roberto
N1 - Publisher Copyright:
Copyright © 2017 by The American Society of Tropical Medicine and Hygiene.
PY - 2017
Y1 - 2017
N2 - Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama. In the past decades, the clinical, epidemiological, pathological, and molecular aspects of OROV have been published and provide the basis for a better understanding of this important human pathogen. Here, we describe the milestones in a comprehensive review of OROV epidemiology, pathogenesis, and molecular biology, including a description of the first isolation of the virus, the outbreaks during the past six decades, clinical aspects of OROV infection, diagnostic methods, genome and genetic traits, evolution, and viral dispersal.
AB - Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama. In the past decades, the clinical, epidemiological, pathological, and molecular aspects of OROV have been published and provide the basis for a better understanding of this important human pathogen. Here, we describe the milestones in a comprehensive review of OROV epidemiology, pathogenesis, and molecular biology, including a description of the first isolation of the virus, the outbreaks during the past six decades, clinical aspects of OROV infection, diagnostic methods, genome and genetic traits, evolution, and viral dispersal.
UR - http://www.scopus.com/inward/record.url?scp=85017116126&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017116126&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.16-0672
DO - 10.4269/ajtmh.16-0672
M3 - Review article
C2 - 28167595
AN - SCOPUS:85017116126
SN - 0002-9637
VL - 96
SP - 1019
EP - 1030
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 5
ER -