Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

Laura C. Fanucchi; Sharon L. Walsh; Alice C. Thornton; Paul A. Nuzzo; Michelle R. Lofwall

doi:10.1093/cid/ciz654

Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

Laura C. Fanucchi, Sharon L. Walsh, Alice C. Thornton, Paul A. Nuzzo, Michelle R. Lofwall

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. Clinical Trials Registration: NCT03048643.

Original language	English
Pages (from-to)	1226-1229
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	70
Issue number	6
DOIs	https://doi.org/10.1093/cid/ciz654
State	Published - Mar 3 2020

Bibliographical note

Publisher Copyright:
© 2019 The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: [email protected].

Keywords

antibiotics
buprenorphine
endocarditis
injection-drug use
opioid-related disorders

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/cid/ciz654

Cite this

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title = "Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections",

abstract = "In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. Clinical Trials Registration: NCT03048643.",

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author = "Fanucchi, {Laura C.} and Walsh, {Sharon L.} and Thornton, {Alice C.} and Nuzzo, {Paul A.} and Lofwall, {Michelle R.}",

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language = "English",

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AU - Walsh, Sharon L.

AU - Thornton, Alice C.

AU - Nuzzo, Paul A.

AU - Lofwall, Michelle R.

N1 - Publisher Copyright: © 2019 The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: [email protected].

PY - 2020/3/3

Y1 - 2020/3/3

N2 - In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. Clinical Trials Registration: NCT03048643.

AB - In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. Clinical Trials Registration: NCT03048643.

KW - antibiotics

KW - buprenorphine

KW - endocarditis

KW - injection-drug use

KW - opioid-related disorders

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Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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