Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

Laura C. Fanucchi, Sharon L. Walsh, Alice C. Thornton, Paul A. Nuzzo, Michelle R. Lofwall

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. Clinical Trials Registration: NCT03048643.

Original languageEnglish
Pages (from-to)1226-1229
Number of pages4
JournalClinical Infectious Diseases
Volume70
Issue number6
DOIs
StatePublished - Mar 3 2020

Bibliographical note

Publisher Copyright:
© 2019 The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: [email protected].

Keywords

  • antibiotics
  • buprenorphine
  • endocarditis
  • injection-drug use
  • opioid-related disorders

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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