Overview of patient compliance with medication dosing: A literature review

Research output: Contribution to journalReview articlepeer-review

416 Scopus citations


The literature was reviewed in an effort to relate frequency of dosing and other influences with patient compliance in medication taking. Once-a-day and twice-a-day regimens were associated with significantly better compliance (73% and 70%, respectively) than were three-times-daily (52%) and four-times-daily (42%) regimens. Compliance is not related to income, social class, occupation, or educational background, and it cannot be accurately predicted by physicians. Unintentional errors in taking medication are made by 50% to 90% of patients.

Original languageEnglish
Pages (from-to)592-599
Number of pages8
JournalClinical Therapeutics
Issue number5
StatePublished - 1984

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


Dive into the research topics of 'Overview of patient compliance with medication dosing: A literature review'. Together they form a unique fingerprint.

Cite this