TY - JOUR
T1 - Oxidative stress, intrauterine growth restriction, and developmental programming of type 2 diabetes
AU - Rashid, Cetewayo S.
AU - Bansal, Amita
AU - Simmons, Rebecca A.
N1 - Publisher Copyright:
© American Physiological Society. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Intrauterine growth restriction (IUGR) leads to reduced birth weight and the development of metabolic diseases such as Type 2 diabetes in adulthood. Mitochondria dysfunction and oxidative stress are commonly found in key tissues (pancreatic islets, liver, and skeletal muscle) of IUGR individuals. In this review, we explore the role of oxidative stress in IUGR-associated diabetes etiology.
AB - Intrauterine growth restriction (IUGR) leads to reduced birth weight and the development of metabolic diseases such as Type 2 diabetes in adulthood. Mitochondria dysfunction and oxidative stress are commonly found in key tissues (pancreatic islets, liver, and skeletal muscle) of IUGR individuals. In this review, we explore the role of oxidative stress in IUGR-associated diabetes etiology.
UR - http://www.scopus.com/inward/record.url?scp=85054778180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85054778180&partnerID=8YFLogxK
U2 - 10.1152/physiol.00023.2018
DO - 10.1152/physiol.00023.2018
M3 - Article
C2 - 30109821
AN - SCOPUS:85054778180
SN - 1548-9213
VL - 33
SP - 348
EP - 359
JO - Physiology
JF - Physiology
IS - 5
ER -
