Intrauterine growth restriction (IUGR) leads to reduced birth weight and the development of metabolic diseases such as Type 2 diabetes in adulthood. Mitochondria dysfunction and oxidative stress are commonly found in key tissues (pancreatic islets, liver, and skeletal muscle) of IUGR individuals. In this review, we explore the role of oxidative stress in IUGR-associated diabetes etiology.
|Number of pages||12|
|State||Published - 2018|
Bibliographical noteFunding Information:
This work was supported by National Institute of Diabetes and Digestive and Kidney Diseases Grant R01 DK-114054.
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