TY - JOUR
T1 - Oxidative stress, osmotic stress and apoptosis
T2 - Impacts on sperm function and preservation in the horse
AU - Ball, Barry A.
PY - 2008/9
Y1 - 2008/9
N2 - Oxidative stress is an important component of the cytopathology of equine spermatozoa undergoing storage as liquid or frozen semen. Damage to chromatin, membranes and proteins of sperm are important components of oxidative damage to sperm. Similarly, sperm are exposed to a variety of osmotic stresses during storage that result from exposure to hypertonic media or result as a consequence of osmotic changes induced during freezing. A number of changes induced during processing and storage of equine sperm also appear to induce apoptotic-like changes which may adversely affect sperm survival and function. These processes appear in many cases to be interrelated, and this review will examine current understanding of these processes on the equine sperm function.
AB - Oxidative stress is an important component of the cytopathology of equine spermatozoa undergoing storage as liquid or frozen semen. Damage to chromatin, membranes and proteins of sperm are important components of oxidative damage to sperm. Similarly, sperm are exposed to a variety of osmotic stresses during storage that result from exposure to hypertonic media or result as a consequence of osmotic changes induced during freezing. A number of changes induced during processing and storage of equine sperm also appear to induce apoptotic-like changes which may adversely affect sperm survival and function. These processes appear in many cases to be interrelated, and this review will examine current understanding of these processes on the equine sperm function.
KW - Apoptosis
KW - Equine
KW - Osmotic stress
KW - Oxidative stress
KW - Sperm
UR - http://www.scopus.com/inward/record.url?scp=47049122193&partnerID=8YFLogxK
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U2 - 10.1016/j.anireprosci.2008.04.014
DO - 10.1016/j.anireprosci.2008.04.014
M3 - Article
C2 - 18524506
AN - SCOPUS:47049122193
SN - 0378-4320
VL - 107
SP - 257
EP - 267
JO - Animal Reproduction Science
JF - Animal Reproduction Science
IS - 3-4
ER -