TY - JOUR
T1 - Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis
AU - Motl, Robert W.
AU - Suh, Yoojin
AU - Dlugonski, Deirdre
AU - Weikert, Madeline
AU - Agiovlasitis, Stamatis
AU - Fernhall, Bo
AU - Goldman, Myla
PY - 2011/4
Y1 - 2011/4
N2 - Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O 2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O 2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.
AB - Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O 2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O 2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.
KW - Multiple sclerosis
KW - Validity
KW - Walking
UR - http://www.scopus.com/inward/record.url?scp=79952898061&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952898061&partnerID=8YFLogxK
U2 - 10.1007/s10072-010-0396-0
DO - 10.1007/s10072-010-0396-0
M3 - Article
C2 - 20798968
AN - SCOPUS:79952898061
SN - 1590-1874
VL - 32
SP - 255
EP - 262
JO - Neurological Sciences
JF - Neurological Sciences
IS - 2
ER -
