Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis

Robert W. Motl; Yoojin Suh; Deirdre Dlugonski; Madeline Weikert; Stamatis Agiovlasitis; Bo Fernhall; Myla Goldman

doi:10.1007/s10072-010-0396-0

Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis

Robert W. Motl
, Yoojin Suh
, Deirdre Dlugonski
, Madeline Weikert
, Stamatis Agiovlasitis
, Bo Fernhall
, Myla Goldman

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O₂ cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O₂ cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O₂ cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O ₂ cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O₂ cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O ₂ cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O₂ cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.

Original language	English
Pages (from-to)	255-262
Number of pages	8
Journal	Neurological Sciences
Volume	32
Issue number	2
DOIs	https://doi.org/10.1007/s10072-010-0396-0
State	Published - Apr 2011

Funding

Funders	Funder number
Institute of Neurological Disorders and Stroke National Advisory Neurological Disorders and Stroke Council	K23NS062898
Institute of Neurological Disorders and Stroke National Advisory Neurological Disorders and Stroke Council

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Multiple sclerosis
Validity
Walking

ASJC Scopus subject areas

Dermatology
Clinical Neurology
Psychiatry and Mental health

Access to Document

10.1007/s10072-010-0396-0

Cite this

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title = "Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis",

abstract = "Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O 2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O 2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.",

keywords = "Multiple sclerosis, Validity, Walking",

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AU - Motl, Robert W.

AU - Suh, Yoojin

AU - Dlugonski, Deirdre

AU - Weikert, Madeline

AU - Agiovlasitis, Stamatis

AU - Fernhall, Bo

AU - Goldman, Myla

PY - 2011/4

Y1 - 2011/4

N2 - Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O 2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O 2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.

AB - Walking impairment is a ubiquitous feature of multiple sclerosis (MS) and the O2 cost of walking might quantify this dysfunction in mild MS. This paper examined the difference in O2 cost of walking between persons with MS who have mild disability and healthy controls and the correlation between the O2 cost of walking and disability. Study 1 included 18 persons with mild MS and 18 controls and indicated that the O 2 cost of walking was significantly higher in MS than controls and that disability was significantly associated with the O2 cost of slow, moderate, and fast treadmill walking. Study 2 included 24 persons with mild MS and indicated that disability was significantly correlated with O 2 cost of comfortable, fast, and slow over-ground walking. We provide evidence that the O2 cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice.

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KW - Validity

KW - Walking

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Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis

Abstract

Funding

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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