Pancreatic Insufficiency: What Is the Gold Standard?

Maisam Abu-El-Haija; Darwin L. Conwell

doi:10.1016/j.giec.2018.05.004

Pancreatic Insufficiency: What Is the Gold Standard?

Maisam Abu-El-Haija, Darwin L. Conwell

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

Original language	English
Pages (from-to)	521-528
Number of pages	8
Journal	Gastrointestinal Endoscopy Clinics of North America
Volume	28
Issue number	4
DOIs	https://doi.org/10.1016/j.giec.2018.05.004
State	Published - Oct 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Inc.

Keywords

Chronic pancreatitis
Endoscopic function testing
Pancreatic function testing
Pancreatic insufficiency

ASJC Scopus subject areas

Gastroenterology

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10.1016/j.giec.2018.05.004

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title = "Pancreatic Insufficiency: What Is the Gold Standard?",

abstract = "Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.",

keywords = "Chronic pancreatitis, Endoscopic function testing, Pancreatic function testing, Pancreatic insufficiency",

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AU - Conwell, Darwin L.

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N2 - Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

AB - Endoscopic pancreatic function testing assesses exocrine insufficiency and chronic pancreatitis. Indirect pancreatic function tests have limited sensitivity and specificity in early disease stages. Magnetic resonance cholangiopancreatography shows promise in detecting early changes as a direct measure of pancreatic function. This article summarizes the evolution of pancreatic function testing and highlights areas for future research, such as development of diagnostic biomarkers to stratify disease severity and targeted therapies to retard disease progression.

KW - Chronic pancreatitis

KW - Endoscopic function testing

KW - Pancreatic function testing

KW - Pancreatic insufficiency

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Pancreatic Insufficiency: What Is the Gold Standard?

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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