Parental occupational exposures and autism spectrum disorder

Erin C. McCanlies; Desta Fekedulegn; Anna Mnatsakanova; Cecil M. Burchfiel; Wayne T. Sanderson; Luenda E. Charles; Irva Hertz-Picciotto

doi:10.1007/s10803-012-1468-1

Parental occupational exposures and autism spectrum disorder

Erin C. McCanlies, Desta Fekedulegn, Anna Mnatsakanova, Cecil M. Burchfiel, Wayne T. Sanderson, Luenda E. Charles, Irva Hertz-Picciotto

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation.

Original language	English
Pages (from-to)	2323-2334
Number of pages	12
Journal	Journal of Autism and Developmental Disorders
Volume	42
Issue number	11
DOIs	https://doi.org/10.1007/s10803-012-1468-1
State	Published - Nov 2012

Bibliographical note

Funding Information:
Acknowledgments The authors would like to thank the families who participated in the CHARGE research project. It is because of their time and commitment that we were able to conduct this research. The authors would also like to thank Lora Delwiche at the University of California, Davis for her help with data management during this project. Grant sponsor: National Institutes of Health, Grant numbers: 1 P01 ES11269, 1 R01 ES015359, Grant sponsor: U.S. Environmental Protection Agency through the Science to Achieve Results (STAR) program, Grant numbers: R829388, R833292.

Keywords

Autism
Autism spectrum disorder
Exposure
Occupation
Parent
Parental exposures

ASJC Scopus subject areas

Developmental and Educational Psychology

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10.1007/s10803-012-1468-1

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abstract = "Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation.",

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note = "Funding Information: Acknowledgments The authors would like to thank the families who participated in the CHARGE research project. It is because of their time and commitment that we were able to conduct this research. The authors would also like to thank Lora Delwiche at the University of California, Davis for her help with data management during this project. Grant sponsor: National Institutes of Health, Grant numbers: 1 P01 ES11269, 1 R01 ES015359, Grant sponsor: U.S. Environmental Protection Agency through the Science to Achieve Results (STAR) program, Grant numbers: R829388, R833292.",

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AU - Charles, Luenda E.

AU - Hertz-Picciotto, Irva

N1 - Funding Information: Acknowledgments The authors would like to thank the families who participated in the CHARGE research project. It is because of their time and commitment that we were able to conduct this research. The authors would also like to thank Lora Delwiche at the University of California, Davis for her help with data management during this project. Grant sponsor: National Institutes of Health, Grant numbers: 1 P01 ES11269, 1 R01 ES015359, Grant sponsor: U.S. Environmental Protection Agency through the Science to Achieve Results (STAR) program, Grant numbers: R829388, R833292.

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Parental occupational exposures and autism spectrum disorder

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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