Periodontal health and disease: The contribution of genetics

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

Periodontitis is an infectious, inflammatory disease that is associated with a complex interplay between specific bacteria, host response, and environmental factors. Because of its high degree of familial aggregation, specifically for the more aggressive forms of the disease, genetics factors have been implicated in disease pathogenesis for several decades. This review provides an overview of what we currently know regarding the genetic and epigenetic contributions to periodontal disease and discusses future opportunities in the field.

Original languageEnglish
Pages (from-to)161-181
Number of pages21
JournalPeriodontology 2000
Volume85
Issue number1
DOIs
StatePublished - Feb 2021

Bibliographical note

Publisher Copyright:
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Keywords

  • epigenetics
  • genetic variation
  • microbiology
  • periodontitis/periodontal disease
  • single nucleotide polymorphism

ASJC Scopus subject areas

  • Periodontics

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