Persistence of Maternal Anti-Rotavirus Immunoglobulin G in the Post-Rotavirus Vaccine Era

Daniel C. Payne, Monica McNeal, Mary Allen Staat, Alexandra M. Piasecki, Allison Cline, Emily Defranco, Michelle G. Goveia, Umesh D. Parashar, Rachel M. Burke, Ardythe L. Morrow

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

To assess whether titers of anti-rotavirus immunoglobulin G persist during the post-rotavirus vaccine era, the Pediatric Respiratory and Enteric Virus Acquisition and Immunogenesis Longitudinal (PREVAIL) Cohort analyzed serum samples collected from Cincinnati-area mothers and young infants in 2017-2018. Rotavirus-specific antibodies continue to be transferred from US mothers to their offspring in the post-rotavirus vaccine era, despite dramatic decreases in childhood rotavirus gastroenteritis.

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalJournal of Infectious Diseases
Volume224
Issue number1
DOIs
StatePublished - Jul 1 2021

Bibliographical note

Publisher Copyright:
© 2020 Published by Oxford University Press for the Infectious Diseases Society of America 2020.

Keywords

  • IgG
  • cohort
  • immunity
  • maternal antibodies
  • rotavirus
  • vaccine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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