Phosphatidylinositol 3-Kinase Inhibition Down-Regulates Survivin and Facilitates TRAIL-Mediated Apoptosis in Neuroblastomas

Medicine and Dentistry

• Programmed Cell Death 100%
• Phosphoinositide 3-Kinase 100%
• Ganglioneuroblastoma 100%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 100%
• Survivin 100%
• Neuroblastoma Cell 33%
• Therapeutic Procedure 22%
• Cells 22%
• Caspase Inhibitor 22%
• LY294002 22%
• Protein Family 22%
• Caspase 3 22%
• Development 11%
• Cell Survival 11%
• Assay 11%
• Enzyme Linked Immunosorbent Assay 11%
• Protein Expression 11%
• Western Blot 11%
• Transient Transfection 11%
• DNA Fragmentation 11%
• Ribonuclease Protection Assay 11%
• Wortmannin 11%
• Therapeutics 11%
• Plasmid 11%

Neuroscience

• Apoptosis 100%
• Neuroblastoma 100%
• Phosphoinositide 3-Kinase 100%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 100%
• Survivin 100%
• Caspase 3 22%
• Caspase 22%
• LY294002 22%
• Inhibitor of Apoptosis Protein 22%
• Protein Family 22%
• ELISA 11%
• Wortmannin 11%
• Protein Expression 11%
• Cell Survival 11%
• Ribonuclease 11%
• Plasmid 11%
• Transient Transfection 11%
• DNA Fragmentation 11%
• Western Blot 11%

Pharmacology, Toxicology and Pharmaceutical Science

• Apoptosis 100%
• Phosphatidylinositol 3 Kinase 100%
• Neuroblastoma 100%
• Survivin 100%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 100%
• 2 Morpholino 8 Phenylchromone 22%
• Caspase Inhibitor 22%
• Inhibitor of Apoptosis Protein 22%
• Caspase 3 22%
• Western Blot 11%
• Enzyme-Linked Immunosorbent Assay 11%
• Survival 11%
• Protein 11%
• DNA 11%
• Ribonuclease 11%
• Wortmannin 11%