Phospholipases D: Making sense of redundancy and duplication

Andrew J. Morris

doi:10.1042/BSR20181883

Phospholipases D: Making sense of redundancy and duplication

Andrew J. Morris

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Why have two genes when one would suffice? Evolutionary pressure means that biology, unlike government, is generally intolerant of wasted effort. Therefore, when multiple genes exist presumably they are there to provide some benefit to the organism even if that benefit is not immediately obvious to us scientists. A recent report from Raghu and colleagues (Biosci. Rep. (2018) 38, pii: BSR20181690) [1] sheds some light on one possible reason for the existence of two Phospholipases D genes in chordates when only one is present in invertebrates.

Original language	English
Article number	BSR20181883
Journal	Bioscience Reports
Volume	39
Issue number	6
DOIs	https://doi.org/10.1042/BSR20181883
State	Published - 2019

Bibliographical note

Publisher Copyright:
© 2019 The Author(s).

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1042/BSR20181883

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AB - Why have two genes when one would suffice? Evolutionary pressure means that biology, unlike government, is generally intolerant of wasted effort. Therefore, when multiple genes exist presumably they are there to provide some benefit to the organism even if that benefit is not immediately obvious to us scientists. A recent report from Raghu and colleagues (Biosci. Rep. (2018) 38, pii: BSR20181690) [1] sheds some light on one possible reason for the existence of two Phospholipases D genes in chordates when only one is present in invertebrates.

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Phospholipases D: Making sense of redundancy and duplication

Abstract

Bibliographical note

ASJC Scopus subject areas

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