Abstract
Two novel strained ruthenium(II) polypyridyl complexes containing a 2,3-dihydro-1,4-dioxino[2,3-f]-1,10-phenanthroline (dop) ligand selectively ejected a methylated ligand when irradiated with >400 nm light. The best compound exhibited a 1880-fold increase in cytotoxicity in human cancer cells upon light-activation and was 19-fold more potent than the well-known chemotherapeutic, cisplatin.
Original language | English |
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Pages (from-to) | 10030-10032 |
Number of pages | 3 |
Journal | Inorganic Chemistry |
Volume | 53 |
Issue number | 19 |
DOIs | |
State | Published - Oct 6 2014 |
Bibliographical note
Publisher Copyright:© 2014 American Chemical Society.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Inorganic Chemistry