Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI

Motomi Ota; Michiaki Kumagai; Yutaka Imai; Younsoo Bae; Yuichi Yamasaki; Masaki Sekino; Shoogo Ueno; Eiji Kaneko; Kentaro Simokado; Kazunori Kataoka

Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI

Motomi Ota, Michiaki Kumagai, Yutaka Imai, Younsoo Bae, Yuichi Yamasaki, Masaki Sekino, Shoogo Ueno, Eiji Kaneko, Kentaro Simokado, Kazunori Kataoka

Pharmaceutical Sciences

Research output: Contribution to conference › Paper › peer-review

Abstract

Poly (ethylene glycol) - poly (amino acid) block copolymer micelles encapsulating magnetite nanoparticles which have high magnetic susceptibility were prepared. Using dynamic light scattering (DLS) measurement of the micelle, we confirmed that the micelle is highly monodisperse in water with the mean size of 100 nm, which is consistent with that observed by TEM analysis (Fig. 1). This micelle retains its original size in 150 mM NaCl solution without aggregation over a week. (Fig.2).

Original language	English
Pages	2072
Number of pages	1
State	Published - 2006
Event	55th SPSJ Annual Meeting - Nagoya, Japan Duration: May 24 2006 → May 26 2006

Conference

Conference	55th SPSJ Annual Meeting
Country/Territory	Japan
City	Nagoya
Period	5/24/06 → 5/26/06

Keywords

Block copolymer micelle
Cancer
Magnetic resonance imaging probes
Magnetite

ASJC Scopus subject areas

Engineering (all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Ota, M., Kumagai, M., Imai, Y., Bae, Y., Yamasaki, Y., Sekino, M., Ueno, S., Kaneko, E., Simokado, K., & Kataoka, K. (2006). Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI. 2072. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.

@conference{d02e5e27b7f54506a325a37e3b221919,

title = "Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI",

abstract = "Poly (ethylene glycol) - poly (amino acid) block copolymer micelles encapsulating magnetite nanoparticles which have high magnetic susceptibility were prepared. Using dynamic light scattering (DLS) measurement of the micelle, we confirmed that the micelle is highly monodisperse in water with the mean size of 100 nm, which is consistent with that observed by TEM analysis (Fig. 1). This micelle retains its original size in 150 mM NaCl solution without aggregation over a week. (Fig.2).",

keywords = "Block copolymer micelle, Cancer, Magnetic resonance imaging probes, Magnetite",

author = "Motomi Ota and Michiaki Kumagai and Yutaka Imai and Younsoo Bae and Yuichi Yamasaki and Masaki Sekino and Shoogo Ueno and Eiji Kaneko and Kentaro Simokado and Kazunori Kataoka",

year = "2006",

language = "English",

pages = "2072",

note = "55th SPSJ Annual Meeting ; Conference date: 24-05-2006 Through 26-05-2006",

}

Ota, M, Kumagai, M, Imai, Y, Bae, Y, Yamasaki, Y, Sekino, M, Ueno, S, Kaneko, E, Simokado, K & Kataoka, K 2006, 'Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI', Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan, 5/24/06 - 5/26/06 pp. 2072.

Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI. / Ota, Motomi; Kumagai, Michiaki; Imai, Yutaka et al.
2006. 2072 Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI

AU - Ota, Motomi

AU - Kumagai, Michiaki

AU - Imai, Yutaka

AU - Bae, Younsoo

AU - Yamasaki, Yuichi

AU - Sekino, Masaki

AU - Ueno, Shoogo

AU - Kaneko, Eiji

AU - Simokado, Kentaro

AU - Kataoka, Kazunori

PY - 2006

Y1 - 2006

N2 - Poly (ethylene glycol) - poly (amino acid) block copolymer micelles encapsulating magnetite nanoparticles which have high magnetic susceptibility were prepared. Using dynamic light scattering (DLS) measurement of the micelle, we confirmed that the micelle is highly monodisperse in water with the mean size of 100 nm, which is consistent with that observed by TEM analysis (Fig. 1). This micelle retains its original size in 150 mM NaCl solution without aggregation over a week. (Fig.2).

AB - Poly (ethylene glycol) - poly (amino acid) block copolymer micelles encapsulating magnetite nanoparticles which have high magnetic susceptibility were prepared. Using dynamic light scattering (DLS) measurement of the micelle, we confirmed that the micelle is highly monodisperse in water with the mean size of 100 nm, which is consistent with that observed by TEM analysis (Fig. 1). This micelle retains its original size in 150 mM NaCl solution without aggregation over a week. (Fig.2).

KW - Block copolymer micelle

KW - Cancer

KW - Magnetic resonance imaging probes

KW - Magnetite

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UR - http://www.scopus.com/inward/citedby.url?scp=33749864870&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33749864870

SP - 2072

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Physicochemical properties of poly(ethylene glycol) - Poly(amino acid) block copolymer micelles encapsulating magnetite nanoparticles and their application to contrast agent for MRI

Abstract

Conference

Keywords

ASJC Scopus subject areas

UN SDGs

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