Pleiotropic mechanisms of virus survival and persistence

Craig S. Miller

doi:10.1016/j.tripleo.2005.03.017

Pleiotropic mechanisms of virus survival and persistence

Craig S. Miller

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Viruses are enormously efficient infectious agents that have been implicated in causing human disease for centuries. Transmission of these pathogens continues to be from one life form to another in the form of isolated cases, epidemics, and pandemics. Each infection requires entry into a susceptible host, replication, and evasion of the immune system. Viruses are successful pathogens because they target specific cells for their attack, exploit the cellular machinery, and are efficient in circumventing and/or inhibiting key cellular events required of survival. This article reviews some of the advances that have taken place in human virology in the past 50 years, emphasizing mechanisms that contribute to, and are involved with, virus survival and persistence.

Original language	English
Pages (from-to)	S27-S36
Journal	Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume	100
Issue number	2 SUPPL.
DOIs	https://doi.org/10.1016/j.tripleo.2005.03.017
State	Published - Aug 2005

Bibliographical note

Funding Information:
This work was supported in part by NIH grant DE14142.

ASJC Scopus subject areas

Surgery
Oral Surgery
Otorhinolaryngology
General Dentistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tripleo.2005.03.017

Cite this

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abstract = "Viruses are enormously efficient infectious agents that have been implicated in causing human disease for centuries. Transmission of these pathogens continues to be from one life form to another in the form of isolated cases, epidemics, and pandemics. Each infection requires entry into a susceptible host, replication, and evasion of the immune system. Viruses are successful pathogens because they target specific cells for their attack, exploit the cellular machinery, and are efficient in circumventing and/or inhibiting key cellular events required of survival. This article reviews some of the advances that have taken place in human virology in the past 50 years, emphasizing mechanisms that contribute to, and are involved with, virus survival and persistence.",

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AB - Viruses are enormously efficient infectious agents that have been implicated in causing human disease for centuries. Transmission of these pathogens continues to be from one life form to another in the form of isolated cases, epidemics, and pandemics. Each infection requires entry into a susceptible host, replication, and evasion of the immune system. Viruses are successful pathogens because they target specific cells for their attack, exploit the cellular machinery, and are efficient in circumventing and/or inhibiting key cellular events required of survival. This article reviews some of the advances that have taken place in human virology in the past 50 years, emphasizing mechanisms that contribute to, and are involved with, virus survival and persistence.

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ER -

Pleiotropic mechanisms of virus survival and persistence

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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