Pleiotropic mechanisms of virus survival and persistence

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Viruses are enormously efficient infectious agents that have been implicated in causing human disease for centuries. Transmission of these pathogens continues to be from one life form to another in the form of isolated cases, epidemics, and pandemics. Each infection requires entry into a susceptible host, replication, and evasion of the immune system. Viruses are successful pathogens because they target specific cells for their attack, exploit the cellular machinery, and are efficient in circumventing and/or inhibiting key cellular events required of survival. This article reviews some of the advances that have taken place in human virology in the past 50 years, emphasizing mechanisms that contribute to, and are involved with, virus survival and persistence.

Original languageEnglish
Pages (from-to)S27-S36
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Issue number2 SUPPL.
StatePublished - Aug 2005

Bibliographical note

Funding Information:
This work was supported in part by NIH grant DE14142.

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology
  • General Dentistry


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