Abstract
Posterior reversible encephalopathy syndrome, an infrequent neurotoxicity associated with the use of tacrolimus, was first described in 1996, as a reversible syndrome manifested by headache, altered mental function, seizures, and visual disturbances. We describe the case of a 37-year-old woman who developed neurologic symptoms consistent with encephalopathy after treatment with tacrolimus, which was prescribed to maintain immunosuppression after orthotopic heart transplantation. This report also discusses the imaging methods used in the diagnosis of posterior reversible encephalopathy and highlights the difficulty of maintaining immunosuppression and managing medication-related adverse effects, while taking into account the risk of acute rejection after transplantation.
Original language | English |
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Pages (from-to) | 205-208 |
Number of pages | 4 |
Journal | Texas Heart Institute Journal |
Volume | 44 |
Issue number | 3 |
DOIs | |
State | Published - Jun 2017 |
Bibliographical note
Publisher Copyright:© 2017 by the Texas Heart ® Institute, Houston
Keywords
- Brain diseases/ diagnostic imaging
- Drug therapy, combination
- Graft rejection/heart transplantation/ adverse effects
- Immunosuppressive agents/ therapeutic use
- Nervous system diseases/chemically induced
- Tacrolimus/adverse effects/therapeutic use
- Treatment outcome
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine