Potential biomarkers for radiosensitivity in head and neck cancers

Sherly Pardo-Reoyo, J. L. Roig-Lopez, Eddy S. Yang

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Radiotherapy is a mainstay of treatment for head and neck cancer. However, the morbidity of treatment remains a clinical challenge. Molecular profiling has provided further insight into tumor biology and tumor sensitivity to radiation, and this information could be used to personalize treatment. In this review, we discuss published signatures of radiosensitivity and discuss the pathways that may be important in dictating radiation sensitivity. Applications of these signatures could result in less morbidity if dose de-escalation efforts are successful.

Original languageEnglish
Article number524
JournalAnnals of Translational Medicine
Issue number24
StatePublished - Dec 2016

Bibliographical note

Publisher Copyright:
© Annals of Translational Medicine. All rights reserved.


  • Biomarkers
  • Epithelial-mesenchymal transition (EMT)
  • Head and neck cancer
  • MicroRNA
  • Radiation sensitivity

ASJC Scopus subject areas

  • General Medicine


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