Abstract
The goal of precision medicine is to deliver the right drug at the right time to the right patient for diagnosis, treatment, and disease monitoring. As technologies have advanced, incorporation of multiple analytes and biomarkers to guide precision medicine-based care is becoming more feasible, especially in the oncology specialty. In this chapter, we discuss next generation sequencing, the practice of precision oncology, and the emergence of the liquid biopsy in the treatment and prognosis of cancer, as well as the clinical utility of incorporating these tests in cancer care.
Original language | English |
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Title of host publication | Comprehensive Precision Medicine, First Edition, Volume 1-2 |
Pages | V1-272-V1-283 |
Volume | 1-2 |
ISBN (Electronic) | 9780128240106 |
DOIs | |
State | Published - Jan 1 2023 |
Bibliographical note
Publisher Copyright:© 2023 Elsevier Inc. All rights reserved.
Keywords
- Biomarkers
- Cancer
- Gene signatures
- Liquid biopsy
- Methylation
- Molecular residual disease
- Mutation
- Next generation sequencing
- Oncogene
- Personalized medicine
- Precision oncology
- Targeted therapy
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology