Predictors of early readmissions in hospitalized patients with gastroparesis: A nationwide analysis

Ravi B. Pavurala, Peter P. Stanich, Somashekar G. Krishna, Praveen Guturu, Alice Hinton, Darwin L. Conwell, Gokulakrishnan Balasubramanian

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background/Aims Gastroparesis is a chronic gastrointestinal disorder that frequently presents with symptoms that are difficult to manage, necessitating frequent hospitalizations. We sought to determine the predictors of early readmission due to gastroparesis based on etiology. Methods We identified all adults discharged with a principal diagnosis of gastroparesis after hospitalization from the 2014 Nationwide Readmission Database. We compared etiology wise (diabetes, post-surgical, and idiopathic) early readmission. Multivariate regression analyses were performed to identify significant predictors of 30-day readmission. Results A total of 12 689 patients were identified, 30.7% diabetic, 2.6% post-surgical, and 66.7% were idiopathic. Patients with diabetic gastroparesis were more likely to be readmitted within 30 days than idiopathic (adjusted odds ratio [aOR], 0.81; 95% confidence interval [CI], 0.69-0.94) and post-surgical gastroparesis (aOR, 0.58; 95% CI, 0.34-0.98). Pyloroplasty was associated with less likelihood of 30-day readmission (aOR, 0.45; 95% CI, 0.20-0.97). In addition, male gender (aOR, 1.18; 95% CI, 1.02-1.37), modified Elixhauser comorbidity score ⪚ 3 (aOR, 1.38; 95% CI, 1.18-1.61), chronic pain syndrome (aOR, 1.41; 95% CI, 1.11-1.78), younger (18-64 years) age (aOR, 1.64; 95% CI, 1.34-2.00), need for percutaneous endoscopic gastrostomy/jejunostomy tube (aOR, 2.06; 95% CI, 1.21-3.52), and need for total parenteral nutrition (aOR, 1.70; 95% CI, 1.24-2.35) were associated with increased risk of 30-day readmission. Conclusions One in 5 patients was readmitted with gastroparesis within 30 days. In the diabetic group, diabetes-related complications contributed to readmissions than gastroparesis. Pyloroplasty is associated with reduced early hospital readmission. Prospective studies are needed for validation of these results.

Original languageEnglish
Pages (from-to)408-418
Number of pages11
JournalJournal of Neurogastroenterology and Motility
Issue number3
StatePublished - Jul 2021

Bibliographical note

Publisher Copyright:
© 2021 The Korean Society of Neurogastroenterology and Motility.


  • Diabetes
  • Diabetes mellitus
  • Gastroparesis
  • Patients readmission

ASJC Scopus subject areas

  • Clinical Neurology
  • Gastroenterology


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