Predictors of surgical site infection after liver resection: A multicentre analysis using National Surgical Quality Improvement Program data

Almudena Moreno Elola-Olaso, Daniel L. Davenport, Jonathan C. Hundley, Michael F. Daily, Roberto Gedaly

Research output: Contribution to journalArticlepeer-review

98 Scopus citations

Abstract

Background: Postoperative infections are frequent complications after liver resection and have significant impact on length of stay, morbidity and mortality. Surgical site infection (SSI) is the most common nosocomial infection in surgical patients, accounting for 38% of all such infections. Objectives: This study aimed to identify predictors of SSI and organ space SSI after liver resection. Methods: Data from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database for patients who underwent liver resection in 2005, 2006 or 2007 in any of 173 hospitals throughout the USA were analysed. All patients who underwent a segmental resection, left hepatectomy, right hepatectomy or trisectionectomy were included. Results: The ACS-NSQIP database contained 2332 patients who underwent hepatectomy during 2005-2007. Rates of SSI varied significantly across primary procedures, ranging from 9.7% in segmental resection patients to 18.3% in trisectionectomy patients. A preoperative open wound, hypernatraemia, hypoalbuminaemia, elevated serum bilirubin, dialysis and longer operative time were independent predictors for SSI and for organ space SSI. Conclusions: These findings may contribute towards the identification of patients at risk for SSI and the development of strategies to reduce the incidence of SSI and subsequent costs after liver resection.

Original languageEnglish
Pages (from-to)136-141
Number of pages6
JournalHPB
Volume14
Issue number2
DOIs
StatePublished - Feb 2012

Keywords

  • hepatectomy
  • organ space infection
  • surgical site infection

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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