Pregnancy-related fibroid reduction

  • Shannon K. Laughlin
  • , Amy H. Herring
  • , David A. Savitz
  • , Andrew F. Olshan
  • , Julia R. Fielding
  • , Katherine E. Hartmann
  • , Donna D. Baird

Research output: Contribution to journalArticlepeer-review

87 Scopus citations

Abstract

We tested the hypothesis that the protective effect of parity on fibroids is due to direct pregnancy-related effects by following women from early pregnancy to postpartum period with ultrasound. Of 171 women with one initial fibroid, 36% had no identifiable fibroid at the time of postpartum ultrasound, and 79% of the remaining fibroids decreased in size.

Original languageEnglish
Pages (from-to)2421-2423
Number of pages3
JournalFertility and Sterility
Volume94
Issue number6
DOIs
StatePublished - Nov 2010

Funding

The work was conducted as part of the Right from the Start study. The parent study received support from the American Water Works Association Research Foundation under contract no. 2579 (D.A.S.); Pfizer Scholars Grants for Faculty Development in Clinical Epidemiology (K.E.H.), and National Institute of Child Health and Human Development Grants RO1 HD043883-04 and HD049675 : “Consequences and Course of Uterine Fibroids in Pregnancy” (K.E.H.). S.K.L. was supported by the National Institutes of Health (NIH) Women's Health Fellowships in Intramural Women's Health Research . The postpartum data collection research was supported in part by the Intramural Research Program of the NIH and the National Institute of Environmental Health Sciences ( P30ES10126 ).

FundersFunder number
Pfizer Scholars Grants for Faculty Development in Clinical Epidemiology
National Institutes of Health (NIH)
National Institutes of Health/National Institute of Environmental Health SciencesP30ES010126
NIH National Institute of Child Health and Human Development National Center for Medical Rehabilitation ResearchHD049675, RO1 HD043883-04
American Water Works Association Research Foundation2579

    Keywords

    • Leiomyoma
    • postpartum
    • pregnancy
    • ultrasound
    • uterine remodeling

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Obstetrics and Gynecology

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