TY - JOUR
T1 - Prematurity and postnatal alterations in intermittent hypoxaemia
AU - DI Fiore, Juliann M.
AU - Shah, Vidhi
AU - Patwardhan, Abhijit
AU - Sattar, Abdus
AU - Wang, Shengxuan
AU - Raffay, Thomas
AU - Martin, Richard J.
AU - Abu Jawdeh, Elie G.
N1 - Publisher Copyright:
©
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life.
AB - Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life.
KW - health services research
KW - neonatology
UR - http://www.scopus.com/inward/record.url?scp=85100875033&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85100875033&partnerID=8YFLogxK
U2 - 10.1136/archdischild-2020-320961
DO - 10.1136/archdischild-2020-320961
M3 - Article
C2 - 33597229
AN - SCOPUS:85100875033
SN - 1359-2998
VL - 106
SP - 557
EP - 559
JO - Archives of Disease in Childhood: Fetal and Neonatal Edition
JF - Archives of Disease in Childhood: Fetal and Neonatal Edition
IS - 5
ER -