Prematurity and postnatal alterations in intermittent hypoxaemia

Juliann M. DI Fiore; Vidhi Shah; Abhijit Patwardhan; Abdus Sattar; Shengxuan Wang; Thomas Raffay; Richard J. Martin; Elie G. Abu Jawdeh

doi:10.1136/archdischild-2020-320961

Prematurity and postnatal alterations in intermittent hypoxaemia

Juliann M. DI Fiore, Vidhi Shah, Abhijit Patwardhan, Abdus Sattar, Shengxuan Wang, Thomas Raffay, Richard J. Martin, Elie G. Abu Jawdeh

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life.

Original language	English
Pages (from-to)	557-559
Number of pages	3
Journal	Archives of Disease in Childhood: Fetal and Neonatal Edition
Volume	106
Issue number	5
DOIs	https://doi.org/10.1136/archdischild-2020-320961
State	Published - Sep 1 2021

Bibliographical note

Funding Information:
Funding The study was funded in part by: (1) The Gerber Foundation, University of Kentucky (EGAJ, PI); (2) University of Kentucky’s National Centre for Advancing Translational Sciences, UL1RR033173; (3) TR is supported by NIH K08HL133459-03 grant; and (4) The Gerber Foundation, Case Western Reserve University (JMDF, coinvestigator; Peter MacFarlane, principal investigator).

Publisher Copyright:
©

Keywords

health services research
neonatology

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1136/archdischild-2020-320961

Cite this

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title = "Prematurity and postnatal alterations in intermittent hypoxaemia",

abstract = "Intermittent hypoxaemia (IH) events are well described in extremely preterm infants, but the occurrence of IH patterns in more mature preterm infants remains unclear. The objective of this study was to characterise the effect of gestational age on early postnatal patterns of IH in extremely (<28 weeks), very (28-<32 weeks) and moderately (32-<34 weeks) preterm infants. As expected, extremely preterm infants had a significantly higher frequency of IH events of longer durations and greater time with hypoxaemia versus very and moderately preterm infants. In addition, the postnatal decrease in IH duration was comparable in the very and moderately preterm infants. This progression of IH events should assist clinicians and families in managing expectations for resolution of IH events during early postnatal life.",

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AU - Sattar, Abdus

AU - Wang, Shengxuan

AU - Raffay, Thomas

AU - Martin, Richard J.

AU - Abu Jawdeh, Elie G.

N1 - Funding Information: Funding The study was funded in part by: (1) The Gerber Foundation, University of Kentucky (EGAJ, PI); (2) University of Kentucky’s National Centre for Advancing Translational Sciences, UL1RR033173; (3) TR is supported by NIH K08HL133459-03 grant; and (4) The Gerber Foundation, Case Western Reserve University (JMDF, coinvestigator; Peter MacFarlane, principal investigator). Publisher Copyright: ©

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Prematurity and postnatal alterations in intermittent hypoxaemia

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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