Prescribing clozapine to 10% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis

Jose de Leon

doi:10.1016/j.euroneuro.2025.112747

Prescribing clozapine to 10% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis

Jose de Leon

Research output: Contribution to journal › Comment/debate

7 Scopus citations

Original language	English
Article number	112747
Number of pages	2
Journal	European Neuropsychopharmacology
Volume	104
DOIs	https://doi.org/10.1016/j.euroneuro.2025.112747
State	Published - Mar 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Clozapine/adverse effects
Clozapine/therapeutic use
Clozapine/toxicity
Mortality/drug effects
Suicide, Attempted
Suicide, Completed

ASJC Scopus subject areas

Pharmacology
Neurology
Clinical Neurology
Psychiatry and Mental health
Biological Psychiatry
Pharmacology (medical)

Access to Document

10.1016/j.euroneuro.2025.112747

Cite this

@article{cd89039cacc54966a6e55bd6062458a8,

title = "Prescribing clozapine to 10\% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis",

keywords = "Clozapine/adverse effects, Clozapine/therapeutic use, Clozapine/toxicity, Mortality/drug effects, Suicide, Attempted, Suicide, Completed",

author = "\{de Leon\}, Jose",

year = "2026",

month = mar,

doi = "10.1016/j.euroneuro.2025.112747",

language = "English",

volume = "104",

}

TY - JOUR

T1 - Prescribing clozapine to 10% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis

AU - de Leon, Jose

PY - 2026/3

Y1 - 2026/3

KW - Clozapine/adverse effects

KW - Clozapine/therapeutic use

KW - Clozapine/toxicity

KW - Mortality/drug effects

KW - Suicide, Attempted

KW - Suicide, Completed

UR - https://www.scopus.com/pages/publications/105025408292

UR - https://www.scopus.com/pages/publications/105025408292#tab=citedBy

U2 - 10.1016/j.euroneuro.2025.112747

DO - 10.1016/j.euroneuro.2025.112747

M3 - Comment/debate

C2 - 41442889

AN - SCOPUS:105025408292

SN - 0924-977X

VL - 104

JO - European Neuropsychopharmacology

JF - European Neuropsychopharmacology

M1 - 112747

ER -

Prescribing clozapine to 10% of patients with schizophrenia may save 320,000 lives and cost 2400 deaths from agranulocytosis

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this