TY - JOUR
T1 - Presumed case of "stiff-horse syndrome" caused by decreased gamma-aminobutyric acid (GABA) production in an American Paint mare
AU - Purcell, Tawna Backman
AU - Sellers, Ann Davidson
AU - Goehring, Lutz S.
PY - 2012/1
Y1 - 2012/1
N2 - Glutamic acid decarboxylase (GAD) converts glutamic acid into the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Increased serum GAD (auto) antibody concentrations were found in a mare with increased postural musculature tone resulting in stiffness and recumbence. The mare was treated with dexamethasone which resulted in resolution of clinical signs and decreased GAD antibody concentrations.
AB - Glutamic acid decarboxylase (GAD) converts glutamic acid into the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Increased serum GAD (auto) antibody concentrations were found in a mare with increased postural musculature tone resulting in stiffness and recumbence. The mare was treated with dexamethasone which resulted in resolution of clinical signs and decreased GAD antibody concentrations.
UR - http://www.scopus.com/inward/record.url?scp=84856623287&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84856623287&partnerID=8YFLogxK
M3 - Article
C2 - 22753968
AN - SCOPUS:84856623287
SN - 0008-5286
VL - 53
SP - 75
EP - 78
JO - Canadian Veterinary Journal
JF - Canadian Veterinary Journal
IS - 1
ER -