TY - JOUR
T1 - Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents
AU - Grines, Cindy L.
AU - Bonow, Robert O.
AU - Casey, Donald E.
AU - Gardner, Timothy J.
AU - Lockhart, Peter B.
AU - Moliterno, David J.
AU - O'Gara, Patrick
AU - Whitlow, Patrick
PY - 2007/5
Y1 - 2007/5
N2 - Background and Overview. Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and health care providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction and death. Conclusions and Clinical Implications. This advisory stresses the importance of 12 months of dual antiplatelet therapy after placement of a drug-eluting stent and educating patients and health care providers about hazards of premature discontinuation. It also recommends post-poning elective surgery for one year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents.
AB - Background and Overview. Dual antiplatelet therapy with aspirin and a thienopyridine has been shown to reduce cardiac events after coronary stenting. However, many patients and health care providers prematurely discontinue dual antiplatelet therapy, which greatly increases the risk of stent thrombosis, myocardial infarction and death. Conclusions and Clinical Implications. This advisory stresses the importance of 12 months of dual antiplatelet therapy after placement of a drug-eluting stent and educating patients and health care providers about hazards of premature discontinuation. It also recommends post-poning elective surgery for one year, and if surgery cannot be deferred, considering the continuation of aspirin during the perioperative period in high-risk patients with drug-eluting stents.
KW - American Heart Association scientific statements
KW - Anticoagulation therapy
KW - Dental care
KW - Myocardial infarction
KW - Myocardial stunning
KW - Stents
KW - Thrombosis
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U2 - 10.14219/jada.archive.2007.0237
DO - 10.14219/jada.archive.2007.0237
M3 - Article
C2 - 17473044
AN - SCOPUS:34249657466
SN - 0002-8177
VL - 138
SP - 652
EP - 655
JO - Journal of the American Dental Association
JF - Journal of the American Dental Association
IS - 5
ER -