Prostatic acid phosphatase, β-glucuronidase and prostate specific antigen assays in fine needle aspirates from benign and malignant prostates

D. R. Erickson, T. C. Hlavinka, A. P. Rockwood, J. D. Metter, D. E. Novicki, M. G. Fried

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Enzymatic assays for tartarate-sensitive acid phosphatase and beta-glucuronidase, and radioimmunoassay for prostate-specific antigen, were modified for application to fine-needle aspirate samples from benign and malignant human prostates. When compared to samples from benign prostates, the ratio of acid phosphatase to beta-glucuronidase activities was significantly decreased in needle aspirates from malignant prostates. Prostate-specific antigen values in the aspirates did not correlate with malignancy.

Original languageEnglish
Pages (from-to)1402-1407
Number of pages6
JournalJournal of Urology
Volume146
Issue number5
DOIs
StatePublished - 1991

Funding

FundersFunder number
National Center for Research ResourcesS07RR005654

    Keywords

    • Acid phosphatase
    • Prostatic neoplasms

    ASJC Scopus subject areas

    • Urology

    Fingerprint

    Dive into the research topics of 'Prostatic acid phosphatase, β-glucuronidase and prostate specific antigen assays in fine needle aspirates from benign and malignant prostates'. Together they form a unique fingerprint.

    Cite this