Proteasome regulation, plant growth and stress tolerance

Jasmina Kurepa, Songhu Wang, Yan Li, Jan Smalle

Research output: Contribution to journalReview articlepeer-review

112 Scopus citations

Abstract

Plant cells contain a mixture of 26S and 20S proteasomes that mediate ubiquitin-dependent and ubiquitin-independent proteolysis, respectively. The 26S proteasome contains the 20S proteasome and one or two regulatory particles that are required for ubiquitin-dependent degradation. Comparative analyses of Arabidopsis proteasome mutants revealed that a decrease in 26S proteasome biogenesis causes heat shock hypersensitivity and reduced cell division rates that are compensated by increased cell expansion. Loss of 26S proteasome function also leads to an increased 20S proteasome biogenesis, which in turn enhances the cellular capacity to degrade oxidized proteins and thus increases oxidative stress tolerance. These findings suggest the intriguing possibility that 26S and 20S proteasome activities are regulated to control plant development and stress responses. This mini-review highlights some of the recent studies on proteasome regulation in plants.

Original languageEnglish
Pages (from-to)924-927
Number of pages4
JournalPlant Signaling and Behavior
Volume4
Issue number10
DOIs
StatePublished - 2009

Keywords

  • Cell division
  • Proteasome
  • Stress responses
  • Ubiquitin-dependent proteolysis
  • Ubiquitin-independent proteolysis

ASJC Scopus subject areas

  • Plant Science

Fingerprint

Dive into the research topics of 'Proteasome regulation, plant growth and stress tolerance'. Together they form a unique fingerprint.

Cite this