At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.
|Number of pages
|Published - Dec 22 2005
Bibliographical noteFunding Information:
The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.
- Salvia divinorum
- Salvinorin A
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology (all)
- Pharmacology, Toxicology and Pharmaceutics (all)