Psychopharmacology of the hallucinogenic sage Salvia divinorum

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99 Scopus citations

Abstract

At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

Original languageEnglish
Pages (from-to)527-531
Number of pages5
JournalLife Sciences
Volume78
Issue number5
DOIs
StatePublished - Dec 22 2005

Bibliographical note

Funding Information:
The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

Keywords

  • Hallucinogen
  • Kappa
  • Opioid
  • Salvia divinorum
  • Salvinorin A

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)
  • Pharmacology, Toxicology and Pharmaceutics (all)

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