Abstract
At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.
Original language | English |
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Pages (from-to) | 527-531 |
Number of pages | 5 |
Journal | Life Sciences |
Volume | 78 |
Issue number | 5 |
DOIs | |
State | Published - Dec 22 2005 |
Bibliographical note
Funding Information:The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.
Funding
The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.
Funders | Funder number |
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Leander J. Valdés III | |
National Institute on Drug Abuse | R01DA018151 |
University of Northern Iowa |
Keywords
- Hallucinogen
- Kappa
- Opioid
- Salvia divinorum
- Salvinorin A
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- General Biochemistry, Genetics and Molecular Biology