Psychopharmacology of the hallucinogenic sage Salvia divinorum

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100 Scopus citations

Abstract

At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

Original languageEnglish
Pages (from-to)527-531
Number of pages5
JournalLife Sciences
Volume78
Issue number5
DOIs
StatePublished - Dec 22 2005

Bibliographical note

Funding Information:
The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

Funding

The author wishes to thank Leander J. Valdés III for a critical reading of the manuscript and the Biological Sciences Funding Program of the University of Iowa and the National Institute on Drug Abuse for financial support of this work.

FundersFunder number
Leander J. Valdés III
National Institute on Drug AbuseR01DA018151
University of Northern Iowa

    Keywords

    • Hallucinogen
    • Kappa
    • Opioid
    • Salvia divinorum
    • Salvinorin A

    ASJC Scopus subject areas

    • General Pharmacology, Toxicology and Pharmaceutics
    • General Biochemistry, Genetics and Molecular Biology

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