Quorum sensing by the Lyme disease spirochete

Brian Stevenson; Kate Von Lackum; Rachel L. Wattier; Jason D. McAlister; Jennifer C. Miller; Kelly Babb

doi:10.1016/S1286-4579(03)00184-9

Quorum sensing by the Lyme disease spirochete

Brian Stevenson, Kate Von Lackum, Rachel L. Wattier, Jason D. McAlister, Jennifer C. Miller, Kelly Babb

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.

Original language	English
Pages (from-to)	991-997
Number of pages	7
Journal	Microbes and Infection
Volume	5
Issue number	11
DOIs	https://doi.org/10.1016/S1286-4579(03)00184-9
State	Published - Sep 2003

Bibliographical note

Funding Information:
Research in our laboratory is funded by U.S. National Institutes of Health grants R01–AI44254, R01–AI53101, and 5T32–AI49795. We thank Natalie Mickelsen for technical assistance and John Carmen for comments on this manuscript.

Keywords

Autoinducer
Borrelia burgdorferi
LuxS
Relapsing fever
Tick

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S1286-4579(03)00184-9

Cite this

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title = "Quorum sensing by the Lyme disease spirochete",

abstract = "The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.",

keywords = "Autoinducer, Borrelia burgdorferi, LuxS, Relapsing fever, Tick",

author = "Brian Stevenson and {Von Lackum}, Kate and Wattier, {Rachel L.} and McAlister, {Jason D.} and Miller, {Jennifer C.} and Kelly Babb",

note = "Funding Information: Research in our laboratory is funded by U.S. National Institutes of Health grants R01–AI44254, R01–AI53101, and 5T32–AI49795. We thank Natalie Mickelsen for technical assistance and John Carmen for comments on this manuscript.",

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T1 - Quorum sensing by the Lyme disease spirochete

AU - Stevenson, Brian

AU - Von Lackum, Kate

AU - Wattier, Rachel L.

AU - McAlister, Jason D.

AU - Miller, Jennifer C.

AU - Babb, Kelly

N1 - Funding Information: Research in our laboratory is funded by U.S. National Institutes of Health grants R01–AI44254, R01–AI53101, and 5T32–AI49795. We thank Natalie Mickelsen for technical assistance and John Carmen for comments on this manuscript.

PY - 2003/9

Y1 - 2003/9

N2 - The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.

AB - The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.

KW - Autoinducer

KW - Borrelia burgdorferi

KW - LuxS

KW - Relapsing fever

KW - Tick

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DO - 10.1016/S1286-4579(03)00184-9

M3 - Review article

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AN - SCOPUS:0041570018

SN - 1286-4579

VL - 5

SP - 991

EP - 997

JO - Microbes and Infection

JF - Microbes and Infection

IS - 11

ER -

Quorum sensing by the Lyme disease spirochete

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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