The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts.
|Number of pages||7|
|Journal||Microbes and Infection|
|State||Published - Sep 2003|
Bibliographical noteFunding Information:
Research in our laboratory is funded by U.S. National Institutes of Health grants R01–AI44254, R01–AI53101, and 5T32–AI49795. We thank Natalie Mickelsen for technical assistance and John Carmen for comments on this manuscript.
- Borrelia burgdorferi
- Relapsing fever
ASJC Scopus subject areas
- Infectious Diseases