@article{87efe6bdc049487580a5a339b68466d7,
title = "Rapid isolation and identification of bacteriophage T4-Encoded modifications of Escherichia coli RNA polymerase: A generic method to study Bacteriophage/Host interactions",
abstract = "Bacteriophages are bacterial viruses that infect bacterial cells, and they have developed ingenious mechanisms to modify the bacterial RNA polymerase. Using a rapid, specific, single-step affinity isolation procedure to purify Escherichia coli RNA polymerase from bacteriophage T4-infected cells, we have identified bacteriophage T4-dependent modifications of the host RNA polymerase. We suggest that this methodology is broadly applicable for the identification of bacteriaphage-dependent alterations of the host synthesis machinery.",
keywords = "Affinityisolation, Bacteriophage, Bacteriophage infection, Coli, Escherichia, MALDI MS, RNA polymerase",
author = "Lars, \{F. Westblade\} and Leonid Minakhin and Konstantin Kuznedelov and Tackett, \{Alan J.\} and Chang, \{Emmanuel J.\} and Mooney, \{Rachel A.\} and Irina Vvedenskaya and Wang, \{Qing Jun\} and David Feny{\"o} and Rout, \{Michael P.\} and Robert Landick and Chait, \{Brian T.\} and Konstantin Severinov and Darst, \{Seth A.\}",
year = "2008",
month = mar,
doi = "10.1021/pr070451j",
language = "English",
volume = "7",
pages = "1244--1250",
number = "3",
}