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Rational design of an enzyme mutant for anti-cocaine therapeutics
Fang Zheng
,
Chang Guo Zhan
Pharmaceutical Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
26
Scopus citations
Overview
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Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Mutant
100%
Butyrylcholinesterase
100%
Cholinesterase
100%
Enzymatic Hydrolysis
50%
Catalytic Mechanism
50%
Metabolic Pathway
33%
Catalytic Efficiency
33%
Development
16%
Metabolite
16%
Molecular Model
16%
Chemistry
Cocaine
100%
Reaction Mechanism
30%
Hydrolysis
23%
Enzymatic Hydrolysis
23%
Structure
15%
Transition State
15%
Group
7%
Rate
7%
Metabolic
7%
Pharmacological Metabolism
7%
Metabolite
7%
Drug Discovery
7%
Procedure
7%
Ester
7%
Arts
7%
Molecular Model
7%
Pharmacology, Toxicology and Pharmaceutical Science
Enzymes
100%
Cocaine
100%
Cholinesterase
50%
Drug Discovery
8%
Drug
8%
Cocaine Dependence
8%
Ester
8%
Engineering
Design
100%
Mechanisms
50%
High Activity
25%
Efficiency
25%
Development
12%
Redesign
12%
State-of-the-Art Technique
12%
Catalyzed Hydrolysis
12%
Mathematical Model
12%