Sodium hydroxymethanesulfinate, (HOCH2SO2Na, HMS) is relatively stable in aqueous alkaline environments, but rapidly decomposes in acidic medium to give a variety of products that include sulfur dioxide. A detailed kinetic and mechanistic study of the decomposition of HMS in slightly acidic medium has shown a process that produces dithionite, S2O2-4, which is preceded by an induction period which persists for as long as molecular oxygen is present in the reaction solution. The complete consumption of molecular oxygen is a prerequisite for the formation of S2O2-4. Among some of the intermediates detected in the decomposition of HMS is the sulfite radical, SO-3. Comparisons are made between the decomposition mechanisms of thiourea dioxide (aminoiminomethanesulfinic acid) and HMS.
|Number of pages||8|
|Journal||Archives of Biochemistry and Biophysics|
|State||Published - Jul 15 1999|
Bibliographical noteFunding Information:
We thank the Ivanovo Academy of Chemistry and Technology for giving a leave of absence to S.V.M. S.V.M. is grateful to the Russian Foundation for Basic Research for financial support (Grant No. 98-03-32802). C.M. is grateful to Steve Leonard for helping with ESR experiments. This work was sponsored by the National Science Foundation (Grant No. CHE-9632592).
- Aminoiminomethanesulfinic acid
- Reactive oxygen species
- Sulfite radical ion
- Sulfoxylate ion
- Sulfur dioxide radical ion
- Thioureas oxides
ASJC Scopus subject areas
- Molecular Biology