Recruitment and Retention Strategies for the D iabetes RE lated to A cute Pancreatitis and Its M echanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium

Cemal Yazici, Anne Marie Dyer, Darwin L. Conwell, Elham Afghani, Dana K. Andersen, Marina Basina, Melena D. Bellin, Leslie R. Boone, Anna Casu, Jeffrey J. Easler, Carla J. Greenbaum, Phil A. Hart, Christie Y. Jeon, Peter J. Lee, Shelby Meier, Georgios I. Papachristou, Nazia T. Raja-Khan, Zeb I. Saeed, Jose Serrano, Dhiraj YadavEvan L. Fogel

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Recruitment and retention of patients with acute pancreatitis (AP) in clinical studies can be challenging. While some obstacles are similar to other clinical conditions, some are unique to AP. Identifying potential barriers early and developing targeted solutions can help optimize recruitment and retention in AP studies. Such pre-emptive and detailed planning can help prospective, longitudinal studies focus on exocrine and endocrine complications of AP in accurately measuring outcomes. This article highlights the challenges in recruitment and retention strategies in AP studies and reviews available resources to create opportunities to address them. We describe the multifaceted approach used by the Recruitment and Retention Committee of the Type 1 Diabetes in Acute Pancreatitis Consortium, which builds upon earlier experiences to develop a recruitment and retention plan for the DREAM (Diabetes RElated to Acute pancreatitis and its Mechanisms) study.

Original languageEnglish
Pages (from-to)598-603
Number of pages6
Issue number6
StatePublished - Jul 1 2022

Bibliographical note

Funding Information:
The study was supported by funding from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC) under award numbers U01 DK127367 (M.D.B.), U01 DK127377 (D.Y.), U01 DK127378 (C.Y.), U01 DK127382 (J.J.E., Z.I.S., E.F.), U01 DK127384 (A.M.D., N.T.R.-K.), U01 DK127388 (D.L.C., P.A.H., G.I.P.), U01 DK127392 (A.C.), U01 DK127395 (M.B.), U01 DK127400 (E.A.), U01 DK127403 (C.Y.J.), and U01 DK127404 (C.J.G.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.


  • AP - acute pancreatitis
  • CRC - clinical research coordinator
  • DCC - data coordinating center
  • DM - diabetes mellitus
  • DREAM - Diabetes RElated to Acute pancreatitis and its Mechanisms
  • EHR - electronic health records
  • IRB - institutional review board
  • NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
  • RIC - recruitment innovation center
  • RRC - recruitment and retention committee
  • T1DAPC - Type 1 Diabetes in Acute Pancreatitis Consortium
  • acute pancreatitis
  • challenges and barriers
  • diabetes
  • enrollment
  • follow-up

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

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