Abstract
Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.
| Original language | English |
|---|---|
| Pages (from-to) | 273-277 |
| Number of pages | 5 |
| Journal | Precision Radiation Oncology |
| Volume | 7 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2023 |
Bibliographical note
Publisher Copyright:© 2023 The Authors. Precision Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Shandong Cancer Hospital & Institute.
Funding
The authors are grateful to the pioneers of our field, Jack Fowler Ph.D. and Luther w Brady M.D. for their guidance in preparing and formulating this concept.
Keywords
- Red Shell
- biological equivalent dose
- normal tissue
- stereotactic radiosurgery
- toxicity
ASJC Scopus subject areas
- Oncology
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