Reduced Risk of Reinfection with SARS-CoV-2 After COVID-19 Vaccination — Kentucky, May-June 2021

Alyson M. Cavanaugh, Kevin B. Spicer, Douglas Thoroughman, Connor Glick, Kathleen Winter

Research output: Contribution to journalArticlepeer-review

163 Citations (SciVal)


What is already known about this topic? Reinfection with human coronaviruses, including SARS-CoV-2, the virus that causes COVID-19, has been documented. Currently, limited evidence concerning the protection afforded by vaccination against reinfection with SARS-CoV-2 is available. What is added by this report? Among Kentucky residents infected with SARS-CoV-2 in 2020, vaccination status of those reinfected during May-June 2021 was compared with that of residents who were not reinfected. In this case-control study, being unvaccinated was associated with 2.34 times the odds of reinfection compared with being fully vaccinated. What are the implications for public health practice? To reduce their likelihood for future infection, all eligible persons should be offered COVID-19 vaccine, even those with previous SARS-CoV-2 infection.

Original languageEnglish
Pages (from-to)1081-1083
Number of pages3
JournalMMWR Recommendations and Reports
Issue number32
StatePublished - 2021

Bibliographical note

Funding Information:
Kentucky's local health departments, disease investigators, and regional epidemiologists; Kentucky Department for Public Health immunization and data team members; Suzanne Beavers, CDC.

Publisher Copyright:
© 2021. All Rights Reserved.

ASJC Scopus subject areas

  • Epidemiology
  • Health(social science)
  • Health, Toxicology and Mutagenesis
  • Health Information Management


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