TY - JOUR
T1 - Reducing perceived barriers to scaling up overdose education and naloxone distribution and medications for opioid use disorder in the United States in the HEALing (helping end addiction long-term®) communities study
AU - Knudsen, Hannah K.
AU - Walker, Daniel M.
AU - Mack, Nicole
AU - Kinnard, Elizabeth N.
AU - Huerta, Timothy R.
AU - Glasgow, La Shawn
AU - Gilbert, Louisa
AU - Garner, Bryan R.
AU - Dasgupta, Anindita
AU - Chandler, Redonna
AU - Walsh, Sharon L.
AU - Tin, Yjuliana
AU - Tan, Sylvia
AU - Sprunger, Joel
AU - Sprague-Martinez, Linda
AU - Salsberry, Pamela
AU - Saucier, Merielle
AU - Rudorf, Maria
AU - Rodriguez, Sandra
AU - Oser, Carrie B.
AU - Oga, Emmanuel
AU - Nakayima, Julie
AU - Linas, Beth S.
AU - Lefebvre, R. Craig
AU - Kosakowski, Sarah
AU - Katz, Rachel E.
AU - Hunt, Timothy
AU - Holman, Ari
AU - Holloway, Ja Nae
AU - Goddard-Eckrich, Dawn
AU - Fareed, Naleef
AU - Christopher, Mia
AU - Aldrich, Alison
AU - Adams, Joella W.
AU - Drainoni, Mari Lynn
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/8
Y1 - 2024/8
N2 - Background: Scaling up overdose education and naloxone distribution (OEND) and medications for opioid use disorder (MOUD) is needed to reduce opioid overdose deaths, but barriers are pervasive. This study examines whether the Communities That HEAL (CTH) intervention reduced perceived barriers to expanding OEND and MOUD in healthcare/behavioral health, criminal-legal, and other/non-traditional venues. Methods: The HEALing (Helping End Addiction Long-Term®) Communities Study is a parallel, wait-list, cluster randomized trial testing the CTH intervention in 67 communities in the United States. Surveys administered to coalition members and key stakeholders measured the magnitude of perceived barriers to scaling up OEND and MOUD in November 2019–January 2020, May–June 2021, and May–June 2022. Multilevel linear mixed models compared Wave 1 (intervention) and Wave 2 (wait-list control) respondents. Interactions by rural/urban status and research site were tested. Results: Wave 1 respondents reported significantly greater reductions in mean scores for three outcomes: perceived barriers to scaling up OEND in Healthcare/Behavioral Health Venues (−0.26, 95% confidence interval, CI: −0.48, −0.05, p = 0.015), OEND in Other/Non-traditional Venues (−0.53, 95% CI: - 0.84, −0.22, p = 0.001) and MOUD in Other/Non-traditional Venues (−0.34, 95% CI: −0.62, −0.05, p = 0.020). There were significant interactions by research site for perceived barriers to scaling up OEND and MOUD in Criminal-Legal Venues. There were no significant interactions by rural/urban status. Discussion: The CTH Intervention reduced perceived barriers to scaling up OEND and MOUD in certain venues, with no difference in effectiveness between rural and urban communities. More research is needed to understand facilitators and barriers in different venues.
AB - Background: Scaling up overdose education and naloxone distribution (OEND) and medications for opioid use disorder (MOUD) is needed to reduce opioid overdose deaths, but barriers are pervasive. This study examines whether the Communities That HEAL (CTH) intervention reduced perceived barriers to expanding OEND and MOUD in healthcare/behavioral health, criminal-legal, and other/non-traditional venues. Methods: The HEALing (Helping End Addiction Long-Term®) Communities Study is a parallel, wait-list, cluster randomized trial testing the CTH intervention in 67 communities in the United States. Surveys administered to coalition members and key stakeholders measured the magnitude of perceived barriers to scaling up OEND and MOUD in November 2019–January 2020, May–June 2021, and May–June 2022. Multilevel linear mixed models compared Wave 1 (intervention) and Wave 2 (wait-list control) respondents. Interactions by rural/urban status and research site were tested. Results: Wave 1 respondents reported significantly greater reductions in mean scores for three outcomes: perceived barriers to scaling up OEND in Healthcare/Behavioral Health Venues (−0.26, 95% confidence interval, CI: −0.48, −0.05, p = 0.015), OEND in Other/Non-traditional Venues (−0.53, 95% CI: - 0.84, −0.22, p = 0.001) and MOUD in Other/Non-traditional Venues (−0.34, 95% CI: −0.62, −0.05, p = 0.020). There were significant interactions by research site for perceived barriers to scaling up OEND and MOUD in Criminal-Legal Venues. There were no significant interactions by rural/urban status. Discussion: The CTH Intervention reduced perceived barriers to scaling up OEND and MOUD in certain venues, with no difference in effectiveness between rural and urban communities. More research is needed to understand facilitators and barriers in different venues.
KW - Community engagement
KW - Implementation science
KW - Medication for opioid use disorder
KW - Naloxone
KW - Opioid epidemic
KW - Opioid overdose
KW - Overdose prevention
UR - http://www.scopus.com/inward/record.url?scp=85195664715&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85195664715&partnerID=8YFLogxK
U2 - 10.1016/j.ypmed.2024.108034
DO - 10.1016/j.ypmed.2024.108034
M3 - Article
C2 - 38857770
AN - SCOPUS:85195664715
SN - 0091-7435
VL - 185
JO - Preventive Medicine
JF - Preventive Medicine
M1 - 108034
ER -
