Abstract
The combination of Cp2TiCl2 with 2 equiv of EtMgBr provides an effective reagent for the reductive cyclization of enynes, including ester-containing enynes, to bicyclic titanacyclopentenes. These metallacycles may then be transformed into bicyclic cyclopentenones or iminocyclopentenes in good yields by reaction with CO or an isocyanide, respectively.
Original language | English |
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Pages (from-to) | 5803-5805 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 57 |
Issue number | 22 |
DOIs | |
State | Published - Oct 1 1992 |
ASJC Scopus subject areas
- Organic Chemistry