Reductive dechlorination of dysidenin from Dysidea herbacea. Structure of a novel binuclear zinc metallocycle

Eugene K. Trousdale, Steven W. Taylor, Sean Parkin, Håkon Hope, Tadeusz F. Molinski

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The structure of a novel 20-membered macrocyclic Zn chelate, prepared by reductive dechlorination of dysidenin, was solved by single crystal X-ray diffraction and confirms the 5S,13S configuration.

Original languageEnglish
Pages (from-to)61-66
Number of pages6
JournalNatural Product Letters
Volume12
Issue number1
DOIs
StatePublished - 1998

Bibliographical note

Funding Information:
This work was partially funded by grants to TFM from the National Sea Grant College Program (R/MP-57A) and the Committee on Research, UC Davis. We thank Dan Jones, Facility of Advanced Instrumentation, for FABMS data and Jeff DeRopp for 500 MHz NMR spectra. The 500 MHz NMR spectrometer was partially funded through NIH ISIO-RR04795 and NSFBBS88-04739.

Keywords

  • Dysidea herbacea
  • Peptide
  • Trichloroleucine
  • X-ray analysis

ASJC Scopus subject areas

  • Molecular Medicine

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