Abstract
Recent results from deep-sequencing and tiling array studies indicated the existence of a large number of short, metabolically stable, non-coding RNAs. Some of these short RNAs derive from known RNA classes like snoRNA or tRNAs. There are intriguing similarities between short non-coding nuclear RNAs and oligonucleotides used to change alternative splicing events, which usually target a disease-relevant RNA. we review the current knowledge of this emerging class of RNAs and discuss evidence that some of these short RNAs could function in alternative splice site selection.
| Original language | English |
|---|---|
| Pages (from-to) | 480-485 |
| Number of pages | 6 |
| Journal | RNA Biology |
| Volume | 7 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2010 |
Bibliographical note
Funding Information:This work was supported by EURASNET and the NIH (GM083187 to S.S.).
Funding
This work was supported by EURASNET and the NIH (GM083187 to S.S.).
| Funders | Funder number |
|---|---|
| EURASNET | |
| National Institutes of Health (NIH) | |
| National Institute of General Medical Sciences | R01GM083187 |
Keywords
- Oligonucleotide
- Prader-Willi syndrome
- Processed snoRNAs
- Small nucleolar RNA
- miRNA
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology
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