Reinforcer pathology theory stipulates that individuals with both (a) high preference for smaller, immediate over larger, delayed rewards; and (b) high demand for unhealthy commodities are uniquely susceptible to poor health outcomes. Specifically, two behavioral economic tasks (delay discounting, assessing preference for smaller, immediate or larger, delayed rewards; and purchasing, assessing purchases of commodities over changes in price) have been independently associated with conditions such as overweight/obesity and problem substance use. In the present study, we examined possible shared neural regions involved in the processes of delay discounting and demand for snack foods in a prediabetic sample. Fifty-four participants completed both of these tasks. Conjunction between delay discounting and purchasing task results indicates substantial common neural substrates recruited during these two tasks, consistent with interpretations of executive control, interoception, and attention, in the prefrontal cortex, insula, and frontoparietal cortex (superior/middle frontal cortex and superior/inferior parietal lobules), respectively. Collectively, these results suggest possible neural substrates in which the two behavioral risk factors of reinforcer pathology may interact during real-world decision-making in prediabetes.
|Number of pages||9|
|Journal||Brain and Cognition|
|State||Published - Jun 2019|
Bibliographical noteFunding Information:
Robert Zivadinov received personal compensation from EMD Serono, Genzyme-Sanofi, Claret Medical and Novartis for speaking and consultant fees. He received financial support for research activities from Genzyme-Sanofi, Novartis, Protembo and Quintiles/IMS.
This research was supported by the National Institutes of Health (NIH) Science of Behavior Change Common Fund Program through an award administered by the National Institute of Diabetes and Digestive and Kidney Diseases (1UH2DK109543-01), awarded to Drs. Epstein and Bickel, and by the National Center for Advancing Translational Sciences under award Number UL1TR001412. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
© 2019 Elsevier Inc.
- Delay discounting
- Reinforcer pathology
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Experimental and Cognitive Psychology
- Developmental and Educational Psychology
- Arts and Humanities (miscellaneous)
- Cognitive Neuroscience