Release of prostaglandin by mitogen and antigen stimulated leukocytes in culture

V. A. Ferraris, F. R. DeRubertis

Research output: Contribution to journalArticlepeer-review

116 Scopus citations

Abstract

The authors demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of prostaglandin E (PGE). The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.

Original languageEnglish
Pages (from-to)378-386
Number of pages9
JournalJournal of Clinical Investigation
Volume54
Issue number2
DOIs
StatePublished - 1974

ASJC Scopus subject areas

  • Medicine (all)

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