Release of prostaglandin by mitogen and antigen stimulated leukocytes in culture

V. A. Ferraris; F. R. DeRubertis

doi:10.1172/JCI107773

Release of prostaglandin by mitogen and antigen stimulated leukocytes in culture

V. A. Ferraris, F. R. DeRubertis

Surgery

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Abstract

The authors demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of prostaglandin E (PGE). The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.

Original language	English
Pages (from-to)	378-386
Number of pages	9
Journal	Journal of Clinical Investigation
Volume	54
Issue number	2
DOIs	https://doi.org/10.1172/JCI107773
State	Published - 1974

ASJC Scopus subject areas

General Medicine

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title = "Release of prostaglandin by mitogen and antigen stimulated leukocytes in culture",

abstract = "The authors demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of prostaglandin E (PGE). The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.",

author = "Ferraris, {V. A.} and DeRubertis, {F. R.}",

year = "1974",

doi = "10.1172/JCI107773",

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AU - Ferraris, V. A.

AU - DeRubertis, F. R.

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N2 - The authors demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of prostaglandin E (PGE). The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.

AB - The authors demonstrate that mitogen and antigen stimulation of leukocytes in culture may be accompanied by enhanced release of prostaglandin E (PGE). The mechanisms mediating this phenomenon and its biologic significance remain to be delineated, but participation of PGE in immunologically induced inflammatory responses seems possible.

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IS - 2

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Release of prostaglandin by mitogen and antigen stimulated leukocytes in culture

Abstract

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