TY - JOUR
T1 - Report of the Pathogenesis and Pathophysiology of Lyme Disease Subcommittee of the HHS Tick Borne Disease Working Group
AU - Donta, Sam T.
AU - States, Leith J.
AU - Adams, Wendy A.
AU - Bankhead, Troy
AU - Baumgarth, Nicole
AU - Embers, Monica E.
AU - Lochhead, Robert B.
AU - Stevenson, Brian
N1 - Publisher Copyright:
© Copyright © 2021 Donta, States, Adams, Bankhead, Baumgarth, Embers, Lochhead and Stevenson.
PY - 2021/6/7
Y1 - 2021/6/7
N2 - An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis and Pathophysiology of Lyme Disease Subcommittee was formed to review what is currently known about the pathogenesis and pathophysiology of Lyme disease, from its inception, but also especially about its ability to persist in the host. To that end, the authors of this report were assembled to update our knowledge about the infectious process, identify the gaps that exist in our understanding of the process, and provide recommendations as to how to best approach solutions that could lead to a better means to manage patients with persistent Lyme disease.
AB - An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis and Pathophysiology of Lyme Disease Subcommittee was formed to review what is currently known about the pathogenesis and pathophysiology of Lyme disease, from its inception, but also especially about its ability to persist in the host. To that end, the authors of this report were assembled to update our knowledge about the infectious process, identify the gaps that exist in our understanding of the process, and provide recommendations as to how to best approach solutions that could lead to a better means to manage patients with persistent Lyme disease.
KW - Lyme disease
KW - health and human services
KW - pathogenesis
KW - pathophysiology
KW - tick borne disease working group
UR - http://www.scopus.com/inward/record.url?scp=85108307616&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85108307616&partnerID=8YFLogxK
U2 - 10.3389/fmed.2021.643235
DO - 10.3389/fmed.2021.643235
M3 - Review article
AN - SCOPUS:85108307616
VL - 8
JO - Frontiers in Medicine
JF - Frontiers in Medicine
M1 - 643235
ER -
