Report of the Pathogenesis and Pathophysiology of Lyme Disease Subcommittee of the HHS Tick Borne Disease Working Group

Sam T. Donta, Leith J. States, Wendy A. Adams, Troy Bankhead, Nicole Baumgarth, Monica E. Embers, Robert B. Lochhead, Brian Stevenson

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis and Pathophysiology of Lyme Disease Subcommittee was formed to review what is currently known about the pathogenesis and pathophysiology of Lyme disease, from its inception, but also especially about its ability to persist in the host. To that end, the authors of this report were assembled to update our knowledge about the infectious process, identify the gaps that exist in our understanding of the process, and provide recommendations as to how to best approach solutions that could lead to a better means to manage patients with persistent Lyme disease.

Original languageEnglish
Article number643235
JournalFrontiers in Medicine
Volume8
DOIs
StatePublished - Jun 7 2021

Bibliographical note

Publisher Copyright:
© Copyright © 2021 Donta, States, Adams, Bankhead, Baumgarth, Embers, Lochhead and Stevenson.

Keywords

  • Lyme disease
  • health and human services
  • pathogenesis
  • pathophysiology
  • tick borne disease working group

ASJC Scopus subject areas

  • General Medicine

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