Reporting data from high-throughput screening of small-molecule libraries

James Inglese, Caroline E. Shamu, R. Kiplin Guy

Research output: Contribution to journalReview articlepeer-review

84 Scopus citations


Publications reporting results of small-molecule screens are becoming more common as academic researchers increasingly make use of high-throughput screening (HTS) facilities. However, no standards have been formally established for reporting small-molecule screening data, and often key information important for the evaluation and interpretation of results is omitted in published HTS protocols. Here, we propose concise guidelines for reporting small-molecule HTS data.

Original languageEnglish
Pages (from-to)438-441
Number of pages4
JournalNature Chemical Biology
Issue number8
StatePublished - Aug 2007

Bibliographical note

Funding Information:
The?authors?are?supported?by?the?US?National? Institutes?of?Health?(NIH)?Roadmap?for?Medical? Research?and?the?Intramural?Research?Program?of? the?NIH?National?Human?Genome?Research?Institute? (J.I.),?by?grants?from?the?NIH?(C.E.S.)?and?by?the? American?Lebanese?and?Syrian? Associated?Charities? (ALSAC)?and?St?Jude?Children’s?Research?Hospital? (R.K.G.).

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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