Abstract
This chapter introduces the basic concepts of fundamental methods for genotype-phenotype association studies and relevant issues in interpretation of genetic epidemiology studies to clinicians. An overview of genetic association studies is provided, which is the current state-of-the-art for clinical and translational genetics. Discussion of future directions in this field is also included.
Original language | English |
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Title of host publication | Essentials of Clinical Research, Second Edition |
Pages | 233-256 |
Number of pages | 24 |
ISBN (Electronic) | 9783319054704 |
DOIs | |
State | Published - Jan 1 2014 |
Keywords
- Familial aggregation
- Genetic research
- Genome-wide association
- Genomics
- Hardy Weinberg disequilibrium
- Linkage disequilibrium
ASJC Scopus subject areas
- Medicine (all)