Residual behavior and dietary risk assessment of albendazole as fungicide in citrus orchards

Lihua Yang, Simin Yao, Anugerah Fajar, Austin Merchant, Jizhe Shi, Haifeng Luo, Zhaoxia Qing, Yaocheng Deng, Xiangwei Tang, Daoxin Gong, Xuguo Zhou

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Albendazole is a broad-spectrum fungicide that shows great potential in controlling fungal diseases in citrus. To quantify the dissipation behavior, residue distribution, and dietary risk of albendazole in citrus, we developed an UPLC-MS/MS analysis protocol. The average recovery rate of albendazole in whole citrus and citrus pulp ranged from 74 to 105% with an RSD of 3 to 8%, and a limit of quantification of 0.01 mg kg−1. The degradation half-lives were 2.8–3.0 and 5.7–17.0 days in whole citrus and citrus pulp, respectively, and the final residues of albendazole were <0.059 mg kg−1 with a risk quotient of <1. This study not only demonstrates that the dietary risk of albendazole in citrus is negligible, but also provides empirical data to establish the maximum residual limit (MRL) for the safe application of albendazole in citrus orchards to meet the requirements for food safety as well as international trade.

Original languageEnglish
Article number135796
JournalFood Chemistry
Volume419
DOIs
StatePublished - Sep 1 2023

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Ltd

Keywords

  • Albendazole
  • Citrus
  • Dietary risk assessment
  • Dissipation behavior
  • Residue distribution
  • UPLC-MS/MS

ASJC Scopus subject areas

  • Analytical Chemistry
  • Food Science

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