TY - JOUR
T1 - Review of Neurologic Comorbidities in Hospitalized Patients With Opioid Abuse
AU - Nelson, Kevin R.
AU - Dolbec, Katelyn
AU - Watson, William
AU - Yuan, Hanwen
AU - Ibraheem, Mam
N1 - Publisher Copyright:
© American Academy of Neurology.
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Purpose of ReviewTo determine the prevalence and burden of neurologic comorbidities in hospitalized patients with opioid abuse.Recent FindingsFrom 1 year of hospital discharges, 2,182 patients with opioid abuse were identified (prevalence 6.3%), with abuse greater among younger patients (p < 0.0001), women (p < 0.0001), Whites (p < 0.0001), and urban population (p = 0.028). Matching for age, sex, race, and urban-rural residence, 347 patients were reviewed, and 179 (52%) had a neurologic comorbidity. The comorbidities frequently overlapped and included encephalopathy (130), neuromuscular disorders (42), seizures (23), spine disorders (23), strokes (20), CNS infections (3), and movement disorders (2). Abuse patients with neurologic comorbidities experienced substantially greater number of hospital and intensive care unit days and mortality, independent of overdose.SummaryNeurologic comorbidities are a frequent and heretofore underappreciated contributor to the disease burden of hospitalized patients with opioid abuse. The importance of neurologic comorbidities should be included in the public health discussions surrounding the opioid epidemic.
AB - Purpose of ReviewTo determine the prevalence and burden of neurologic comorbidities in hospitalized patients with opioid abuse.Recent FindingsFrom 1 year of hospital discharges, 2,182 patients with opioid abuse were identified (prevalence 6.3%), with abuse greater among younger patients (p < 0.0001), women (p < 0.0001), Whites (p < 0.0001), and urban population (p = 0.028). Matching for age, sex, race, and urban-rural residence, 347 patients were reviewed, and 179 (52%) had a neurologic comorbidity. The comorbidities frequently overlapped and included encephalopathy (130), neuromuscular disorders (42), seizures (23), spine disorders (23), strokes (20), CNS infections (3), and movement disorders (2). Abuse patients with neurologic comorbidities experienced substantially greater number of hospital and intensive care unit days and mortality, independent of overdose.SummaryNeurologic comorbidities are a frequent and heretofore underappreciated contributor to the disease burden of hospitalized patients with opioid abuse. The importance of neurologic comorbidities should be included in the public health discussions surrounding the opioid epidemic.
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U2 - 10.1212/CPJ.0000000000001080
DO - 10.1212/CPJ.0000000000001080
M3 - Review article
AN - SCOPUS:85163818894
SN - 2163-0402
VL - 11
SP - 527
EP - 533
JO - Neurology: Clinical Practice
JF - Neurology: Clinical Practice
IS - 6
ER -