Abstract
The CCCH class of zinc fingers occurs in a large number of Arabidopsis proteins. Previous studies revealed that one such protein is a nuclease, the activity of which is attributable to one of the CCCH motifs. To examine whether nuclease activity is a more general characteristic of CCCH zinc finger containing proteins, five other such Arabidopsis proteins were assayed for a similar activity. The results indicate that all of these proteins possess nuclease activity. Thus, nuclease activity may be a common characteristic of Arabidopsis CCCH-containing proteins.
Original language | English |
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Pages (from-to) | 2577-2582 |
Number of pages | 6 |
Journal | FEBS Letters |
Volume | 582 |
Issue number | 17 |
DOIs | |
State | Published - Jul 23 2008 |
Bibliographical note
Funding Information:The authors thank Carol Von Lanken for excellent technical and administrative support. This work was supported by NSF Arabidopsis 2010 Grant MCB-0313472.
Keywords
- Polyadenylation
- RNA binding
- Ribonuclease
- Zinc-finger protein
ASJC Scopus subject areas
- Biophysics
- Structural Biology
- Biochemistry
- Molecular Biology
- Genetics
- Cell Biology