The CCCH class of zinc fingers occurs in a large number of Arabidopsis proteins. Previous studies revealed that one such protein is a nuclease, the activity of which is attributable to one of the CCCH motifs. To examine whether nuclease activity is a more general characteristic of CCCH zinc finger containing proteins, five other such Arabidopsis proteins were assayed for a similar activity. The results indicate that all of these proteins possess nuclease activity. Thus, nuclease activity may be a common characteristic of Arabidopsis CCCH-containing proteins.
|Number of pages||6|
|State||Published - Jul 23 2008|
Bibliographical noteFunding Information:
The authors thank Carol Von Lanken for excellent technical and administrative support. This work was supported by NSF Arabidopsis 2010 Grant MCB-0313472.
- RNA binding
- Zinc-finger protein
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology
- Cell Biology